Endoscopic management of pancreatic walled-off necrosis

Ann Gastroenterol. 2023 Mar-Apr;36(2):123-131. doi: 10.20524/aog.2023.0772. Epub 2023 Jan 4.

Abstract

Pancreatic walled-off necrosis (WON) is a complication of severe pancreatitis. Endoscopic transmural drainage has been recognized as the first-line treatment for pancreatic fluid collections. Endoscopy offers a minimally invasive approach when compared to surgical drainage. Today, endoscopists may choose to use self-expanding metal stents, pigtail stents, or lumen-apposing metal stents to facilitate drainage of fluid collections. Current data suggest that all 3 approaches yield similar outcomes. It was previously thought that drainage should be performed 4 weeks from the initial event of pancreatitis, theoretically allowing the capsule to mature. However, current data show that both early (<4 weeks) and standard (≥4 weeks) endoscopic drainage are comparable. Herein, we provide an up-to-date state-of-the-art review of the indications, techniques, innovations, outcomes, and future perspectives following drainage of pancreatic WON.

Keywords: Pancreatitis; endoscopic transmural drainage; pancreatic fluid collection; stent; walled-off necrosis.

Publication types

  • Review