Fibrothecoma of broad ligament with minor sex cord elements: Case report and brief literature review

Medicine (Baltimore). 2023 Mar 3;102(9):e33127. doi: 10.1097/MD.0000000000033127.

Abstract

Rationale: Sex cord-stromal tumors are always found in ovary, but the occurrence of this kind of tumor at extraovarian locations is extremely rare. Up to now, the case concerning fibrothecoma of broad ligament with minor sex cord elements has not been reported, and it is extremely challenging to diagnose before surgery. In this case report, we summarized pathogenesis, clinical features, laboratory finding, imaging studies, pathology, and therapeutic schedule of this tumor, with the aim of raising awareness and attention to this type of disease.

Patient concerns: A 45-year-old Chinese woman was referred to our department with intermittent lower abdominal pain for about 6 years. On examination, both ultrasonography and computed tomography revealed she had a right adnexal mass.

Diagnosis: Based on the results of histology and immunohistochemistry, the final diagnosis was confirmed as fibrothecoma of broad ligament with minor sex cord elements.

Interventions: This patient underwent laparoscopic unilateral salpingo-oophorectomy with excision of the neoplasm.

Outcomes: Eleven days post-treatment, the patient complained that the symptoms of abdominal pain was disappeared. There is no evidence of disease recurrence 5 years after laparoscopic surgery according to the consequences of radiologic examination.

Conclusion: The natural history of this kind of tumor is uncertain. Although main treatment of this neoplasm might be surgical resection and good prognosis can be achieved, we believe that long-time follow-up is extremely important in all patients diagnosed as fibrothecoma of broad ligament with minor sex cord. Laparoscopic unilateral salpingo-oophorectomy with excision of the tumor should be recommended to these patients.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abdominal Pain / etiology
  • Broad Ligament* / surgery
  • Female
  • Fibroma* / complications
  • Fibroma* / diagnostic imaging
  • Fibroma* / pathology
  • Fibroma* / surgery
  • Humans
  • Laparoscopy
  • Middle Aged
  • Ovariectomy
  • Salpingectomy
  • Sex Cord-Gonadal Stromal Tumors* / complications
  • Sex Cord-Gonadal Stromal Tumors* / diagnostic imaging
  • Sex Cord-Gonadal Stromal Tumors* / pathology
  • Sex Cord-Gonadal Stromal Tumors* / surgery
  • Thecoma* / complications
  • Thecoma* / diagnostic imaging
  • Thecoma* / pathology
  • Thecoma* / surgery
  • Tomography, X-Ray Computed
  • Ultrasonography