Identification of compounds present in lipophilic extracts from Brachystola magna (Girard): substances with potential healing properties

Nat Prod Res. 2024 Feb-Mar;38(4):639-643. doi: 10.1080/14786419.2023.2180637. Epub 2023 Feb 21.

Abstract

Insects from the Orthoptera order possess important biological activities such as wound healing and represent a therapeutic resource in traditional medicine worldwide. Hence, this study addressed the characterisation of lipophilic extracts from Brachystola magna (Girard), identifying compounds with potential healing properties. For that, four extracts were obtained from sample 1 (head-legs) and sample 2 (abdomen): extract A (hexane/sample 1), extract B (hexane/sample 2), extract C (ethyl acetate/sample 1) and extract D (ethyl acetate/sample 2). All extracts were analysed by Gas Chromatography-Mass Spectrometry (GC-MS), Gas Chromatography-Flame Ionization Detection (GC-FID) and Fourier-Transform Infrared Spectroscopy (FTIR). Compounds identified were squalene, cholesterol and fatty acids, having a higher concentration of linolenic acid in extracts A and B, while extracts C and D had a higher content of palmitic acid. Additionally, FTIR detected characteristic peaks of lipids and triglycerides. Components of the lipophilic extracts suggested that this product could be used for skin illnesses treatment.

Keywords: Brachystola magna (Girard); entomology; fatty acids; lipophilic extracts.

MeSH terms

  • Acetates
  • Gas Chromatography-Mass Spectrometry
  • Hexanes* / chemistry
  • Plant Extracts* / chemistry
  • Plant Extracts* / pharmacology

Substances

  • ethyl acetate
  • Plant Extracts
  • Hexanes
  • Acetates