CRISPR/Cas genome editing system and its application in potato

Xin Hou; Xiaomeng Guo; Yan Zhang; Qiang Zhang

doi:10.3389/fgene.2023.1017388

CRISPR/Cas genome editing system and its application in potato

Front Genet. 2023 Feb 13:14:1017388. doi: 10.3389/fgene.2023.1017388. eCollection 2023.

Authors

Xin Hou¹, Xiaomeng Guo¹, Yan Zhang¹, Qiang Zhang¹

Affiliation

¹ College of Plant Protection, Shandong Agricultural University, Tai'an, China.

Abstract

Potato is the largest non-cereal food crop worldwide and a vital substitute for cereal crops, considering its high yield and great nutritive value. It plays an important role in food security. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system has the advantages of easy operation, high efficiency, and low cost, which shows a potential in potato breeding. In this paper, the action mechanism and derivative types of the CRISPR/Cas system and the application of the CRISPR/Cas system in improving the quality and resistance of potatoes, as well as overcoming the self-incompatibility of potatoes, are reviewed in detail. At the same time, the application of the CRISPR/Cas system in the future development of the potato industry was analyzed and prospected.

Keywords: CRISPR/Cas; gene editing; genetic improvement; potato; progress.

Publication types

Review

Grants and funding

The study was supported by the Shandong Weifang Tobacco Company Science and Technology Project (2022-26), the China Tobacco Shandong Industrial Corporation Science and Technology Project (202102004), and the Shandong Province Modern Agricultural Technology System (SDAIT-25-02).