Risk factor analysis of omicron patients with mental health problems in the Fangcang shelter hospital based on psychiatric drug intervention during the COVID-19 pandemic in Shanghai, China

Ping Yu; Xiaolan Bian; Zhihui Xie; Xu Wang; Xujing Zhang; Zhidong Gu; Zhitao Yang; Feng Jing; Weiyu Qiu; Jingsheng Lin; Jie Tang; Chen Huang; Yibo Zhang; Ying Chen; Zongfeng Zhang; Yufang Bi; Hanbing Shang; Erzhen Chen

doi:10.3389/fpsyt.2023.1100849

Risk factor analysis of omicron patients with mental health problems in the Fangcang shelter hospital based on psychiatric drug intervention during the COVID-19 pandemic in Shanghai, China

Front Psychiatry. 2023 Feb 13:14:1100849. doi: 10.3389/fpsyt.2023.1100849. eCollection 2023.

Authors

Ping Yu¹, Xiaolan Bian¹, Zhihui Xie², Xu Wang³, Xujing Zhang⁴, Zhidong Gu⁵, Zhitao Yang⁶, Feng Jing⁶, Weiyu Qiu¹, Jingsheng Lin⁷, Jie Tang⁷, Chen Huang⁶, Yibo Zhang⁸, Ying Chen⁶, Zongfeng Zhang⁹, Yufang Bi¹⁰, Hanbing Shang^{5

11}, Erzhen Chen⁶

Affiliations

¹ Department of Pharmacy, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Department of Medical Affairs, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
³ Department of Asset Management, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁴ Department of Foreign Cooperation and Development, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁵ Ruijin-Hainan Hospital, Shanghai Jiao Tong University School of Medicine, Bo'ao Research Hospital, Qionghai, Hainan, China.
⁶ Department of Emergency, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁷ Department of Disciplinary Development and Planning, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁸ Department of Hospital-infection Control, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁹ Department of Psychiatry, Ningbo Kangning Hospital, Ningbo, Zhejiang, China.
¹⁰ Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
¹¹ Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Abstract

Backgrounds: The widespread coronavirus disease 2019 (COVID-19) outbreak impacted the mental health of infected patients admitted to Fangcang shelter hospital a large-scale, temporary structure converted from existing public venues to isolate patients with mild or moderate symptoms of COVID-19 infection.

Objective: This study aimed to investigate the risk factors of the infected patients from a new pharmacological perspective based on psychiatric drug consumption rather than questionnaires for the first time.

Methods: We summarised the medical information and analysed the prevalence proportion, characteristics, and the related risk factors of omicron variants infected patients in the Fangcang Shelter Hospital of the National Exhibition and Convention Center (Shanghai) from 9 April 2022 to 31 May 2022.

Results: In this study, 6,218 individuals at 3.57% of all admitted patients in the Fangcang shelter were collected suffering from mental health problems in severe conditions including schizophrenia, depression, insomnia, and anxiety who needed psychiatric drug intervention. In the group, 97.44% experienced their first prescription of psychiatric drugs and had no diagnosed historical psychiatric diseases. Further analysis indicated that female sex, no vaccination, older age, longer hospitalization time, and more comorbidities were independent risk factors for the drug-intervened patients.

Conclusion: This is the first study to analyse the mental health problems of omicron variants infected patients hospitalised in Fangcang shelter hospitals. The research demonstrated the necessity of potential mental and psychological service development in Fangcang shelters during the COVID-19 pandemic and other public emergency responses.

Keywords: COVID-19; Fangcang shelter hospital; mental health; psychiatric drugs intervention; public health.