In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks

Russell M Main; Simon M Vornholt; Cameron M Rice; Caroline Elliott; Samantha E Russell; Peter J Kerr; Mark R Warren; Russell E Morris

doi:10.1038/s42004-023-00845-1

In situ single-crystal synchrotron X-ray diffraction studies of biologically active gases in metal-organic frameworks

Commun Chem. 2023 Mar 1;6(1):44. doi: 10.1038/s42004-023-00845-1.

Authors

Russell M Main¹, Simon M Vornholt², Cameron M Rice¹, Caroline Elliott¹, Samantha E Russell¹, Peter J Kerr¹, Mark R Warren³, Russell E Morris⁴

Affiliations

¹ EaStCHEM School of Chemistry, Purdie Building, North Haugh, St Andrews, KY16 9ST, UK.
² Department of Chemistry, SUNY Stony Brook, 100 Nicolls Road, 104 Chemistry, Stony Brook, NY, 11790-3400, USA.
³ Diamond Light Source Ltd, Diamond House, Harwell Science & Innovation Campus, Didcot, OX11 0DE, UK.
⁴ EaStCHEM School of Chemistry, Purdie Building, North Haugh, St Andrews, KY16 9ST, UK. rem1@st-andrews.ac.uk.

Abstract

Metal-organic frameworks (MOFs) are well known for their ability to adsorb various gases. The use of MOFs for the storage and release of biologically active gases, particularly nitric oxide (NO) and carbon monoxide (CO), has been a subject of interest. To elucidate the binding mechanisms and geometry of these gases, an in situ single crystal X-ray diffraction (scXRD) study using synchrotron radiation at Diamond Light Source has been performed on a set of MOFs that display promising gas adsorption properties. NO and CO, were introduced into activated Ni-CPO-27 and the related Co-4,6-dihydroxyisophthalate (Co-4,6-dhip). Both MOFs show strong binding affinity towards CO and NO, however CO suffers more from competitive co-adsorption of water. Additionally, we show that morphology can play an important role in the ease of dehydration for these two systems.

Abstract

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