In recent years, acupuncture has gained great progress in the treatment of chronic respiratory diseases (CRD), and the clinical effect is remarkable, but its underlying mechanisms are relatively complex, with the anti-inflammatory effect being the primary aspect. Based on the literature both at home and abroad, we found that the anti-inflammatory mechanism of acupuncture mainly involves chemokines, kinase-related pathways, helper T cells, epigenetic modification, autophagy, vagal-mediated cholinergic anti-inflammatory pathway, etc. The researches on some anti-inflammatory mechanisms are still in the initial stage, the relationship among various pathways, and the key factors affecting the effect of acupuncture, such as acupoint selection, stimulation intensity and needling depth, etc. warrant further exploration in the future.
针灸治疗慢性呼吸系统疾病的机制较为复杂，其中抗炎相关机制是首要作用途径。基于国内外文献，我们对目前现有的研究进行归纳发现，针灸治疗慢性呼吸系统疾病的抗炎机制主要集中在趋化因子、激酶相关通路、辅助性T细胞、表观遗传修饰、自噬、迷走神经介导的胆碱能抗炎途径等方面。通过对这些抗炎机制的归纳及展望，本文将为针灸治疗慢性呼吸系统疾病的深入机制研究提供一定的依据和思路。.
Keywords: Acupuncture; Anti-inflammation mechanism; Chronic respiratory diseases; Review.