Compared between support vector machine (SVM) and deep belief network (DBN) for multi-classification of Raman spectroscopy for cervical diseases

Photodiagnosis Photodyn Ther. 2023 Jun:42:103340. doi: 10.1016/j.pdpdt.2023.103340. Epub 2023 Feb 27.

Abstract

In this study, a minimally invasive test method for cervical cancer in vitro was proposed by comparing Raman spectroscopy with support vector machine (SVM) model and deep belief network (DBN) model. The serum Raman spectra of cervical cancer, hysteromyoma, and healthy people were collected. After data processing, SVM classification model and DBN classification model were built respectively. The experimental results show that when the DBN network algorithm is used, the sample test set can be divided accurately and the result of cross-validation is ideal. Compared with the traditional SVM algorithm, this method firstly screened the effective feature matrix from the data, and then classified the data. With high efficiency and accuracy, based on 445 samples collected, this method improved the accuracy by 13.93%±2.47% compared with the SVM method, and provided a new direction and idea for the in vitro diagnosis of cervical diseases.

Keywords: Cervical cancer; Deep belief network; Diagnosis; Hysteromyoma; Raman spectroscopy; Support vector machine (SVM).

MeSH terms

  • Female
  • Humans
  • Photochemotherapy* / methods
  • Photosensitizing Agents
  • Spectrum Analysis, Raman / methods
  • Support Vector Machine
  • Uterine Cervical Neoplasms* / diagnosis

Substances

  • Photosensitizing Agents