Converting commonly-used paper into nano-engineered fluorescent biomass-based platform for rapid ClO- quantitative detection in living cells and water sources

Nihao Li; Huie Jiang; Lijuan Chen; Zhijian Li; Qingxin Han; Lulu Ning; Zhenjuan Chen; Suqiu Zhao; Xinhua Liu

doi:10.1016/j.chemosphere.2023.138227

Converting commonly-used paper into nano-engineered fluorescent biomass-based platform for rapid ClO^- quantitative detection in living cells and water sources

Chemosphere. 2023 May:324:138227. doi: 10.1016/j.chemosphere.2023.138227. Epub 2023 Feb 27.

Authors

Nihao Li¹, Huie Jiang², Lijuan Chen³, Zhijian Li⁴, Qingxin Han³, Lulu Ning¹, Zhenjuan Chen¹, Suqiu Zhao¹, Xinhua Liu⁵

Affiliations

¹ College of Bioresources Chemistry and Materials Engineering, National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science and Technology, Xi'an, 710021, PR China.
² College of Bioresources Chemistry and Materials Engineering, National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science and Technology, Xi'an, 710021, PR China. Electronic address: jianghuie@sust.edu.cn.
³ Institute of Biomass & Functional Materials, Shaanxi University of Science &Technology, Xi'an, 710021, PR China.
⁴ College of Bioresources Chemistry and Materials Engineering, National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science and Technology, Xi'an, 710021, PR China. Electronic address: lizj@sust.edu.cn.
⁵ Institute of Biomass & Functional Materials, Shaanxi University of Science &Technology, Xi'an, 710021, PR China. Electronic address: liuxinhua@sust.edu.cn.

PMID: 36858120
DOI: 10.1016/j.chemosphere.2023.138227

Abstract

Hypochlorous acid (HClO) and derivative ionic form (ClO^-) are significant components of reactive oxygen species, and thus various diseases are correlatively related to the concentration of ClO^-. Recently, paper-based indicators have been confirmed to be efficient strategy for sensing hazardous and noxious substances. However, most of these materials can only achieve qualitative detection of the substrates. Herein, an extremely simple manufacturing strategy was proposed to convert commonly-used paper into nano-engineered fluorescent biomass-based platform (CMJL-FP) integrated with on-demand self-assembled colorimetric and ratiometric fluorescence sensor (CMJL) for rapid ClO^- quantitative detection in organisms or water sources using smartphones. The CMJL exhibited a highly selective and sensitive ratiometric response to ClO^- at a low detection limit (LOD = 92.6 nM). The associating interactions between the fluorescence nano-particles and micro-nano fibers of CMJL-FP ensure good-stability during ClO^- detection. It has been experimentally demonstrated that CMJL-FP allows one to realize the rapid quantitative detection of ClO^- ions in living cells and large-scale water sources by using color recognition software as part of a simple smartphone. Therefore, integrating the proposed fluorescent paper with smartphones provides an effective, sustainable, cheap and conceptual strategy for quantitative detection of hazardous and noxious substances in organisms and environments.

Keywords: Hypochlorite ions; Paper-based functional materials; Quantitative detection; Smartphone.

MeSH terms

Biomass
Colorimetry
Fluorescent Dyes* / chemistry
Hypochlorous Acid / chemistry
Ions
Water*

Substances

Fluorescent Dyes
Water
Hypochlorous Acid
Ions