Nanotechnology in Lung Cancer Therapeutics: A Narrative Review

Vaibhav Koutu; Manish Gupta; Saikat Das; Deepak K Rawat; Vipin Kharade; Rajesh K Pasricha

doi:10.7759/cureus.34245

Nanotechnology in Lung Cancer Therapeutics: A Narrative Review

Cureus. 2023 Jan 26;15(1):e34245. doi: 10.7759/cureus.34245. eCollection 2023 Jan.

Authors

Vaibhav Koutu¹, Manish Gupta¹, Saikat Das¹, Deepak K Rawat¹, Vipin Kharade¹, Rajesh K Pasricha¹

Affiliation

¹ Radiotherapy, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

Abstract

To date, cancer continues to be one of the biggest challenges for medical science. Nanotechnology has enabled us to overcome some of the limitations of conventional treatment in lung cancer therapeutics. Recently, US Food and Drug Administration (FDA) has approved certain nanomedicines for clinical administration against lung cancer. This article presents a narrative review of approved nanomedicines in lung cancer with a special focus on the results of recently concluded and ongoing clinical trials. The limitations associated with using nanomaterials as anti-lung cancer therapeutic agents and the possible mechanisms to overcome these limitations are also discussed.

Keywords: drug delivery; lung cancer; nanomaterials; nanomedicines; therapeutics.

Publication types

Review

Grants and funding

The authors thank the Department of Science and Technology (DST), a department within the Ministry of Science and Technology under the Government of India (GoI), for funding the project under the Biomedical Device and Technology Development (BDTD) scheme.