Clinical study of complications of a peripherally inserted central catheter in cancer patients

Nurs Open. 2023 Jul;10(7):4480-4489. doi: 10.1002/nop2.1690. Epub 2023 Feb 28.

Abstract

Aim: To evaluate complications after PICC use in cancer patients.

Design: This was a clinical and retrospective study in which the risk factors and complications of PICC use were evaluated.

Methods: This study was carried out in the patient, emergency room, and intensive care units through the evaluation of electronic medical records. To assess the association between qualitative variables, the chi-squared test or Fisher's exact test was used, and to compare the reason for withdrawal, the Kruskal-Wallis test was applied.

Results: A total of 359 patients (53.5% men) with 43.1 ± 14 years who had a PICC (88% with solid tumours) were evaluated. The most common complications were mechanical complications (61.2%), infection (38%), and thrombosis (57.1%). Patients with double-lumen catheters experienced thrombosis (85.7%). This study demonstrated the effectiveness of PICC and that patients with haematological cancer are more prone to multiple PICC passages and more mechanical complications and infections.

Keywords: catheters; neoplasms; observational study; peripheral catheterization; retrospective study; risk factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catheter-Related Infections* / complications
  • Catheter-Related Infections* / etiology
  • Catheterization, Central Venous* / adverse effects
  • Central Venous Catheters* / adverse effects
  • Female
  • Hematologic Neoplasms* / complications
  • Humans
  • Male
  • Retrospective Studies
  • Thrombosis* / etiology