Solvent-free mechanochemical multicomponent preparation of 4H-pyrans catalyzed by Cu2(NH2-BDC)2(DABCO) metal-organic framework

Zahra Akhlaghi; Mohammad R Naimi-Jamal; Leila Panahi; Mohammad G Dekamin; Bahareh Farasati Far

doi:10.1016/j.heliyon.2023.e13522

Solvent-free mechanochemical multicomponent preparation of 4H-pyrans catalyzed by Cu₂(NH₂-BDC)₂(DABCO) metal-organic framework

Heliyon. 2023 Feb 8;9(2):e13522. doi: 10.1016/j.heliyon.2023.e13522. eCollection 2023 Feb.

Authors

Zahra Akhlaghi¹, Mohammad R Naimi-Jamal¹, Leila Panahi¹, Mohammad G Dekamin², Bahareh Farasati Far¹

Affiliations

¹ Research Laboratory of Green Organic Synthesis and Polymers, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran.
² Pharmaceutical and Heterocyclic Compounds Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846-13114 Tehran, Iran.

Abstract

4H-pyrans have been prepared through a mechanochemical multicomponent reaction (MCR) of different aldehydes, malononitrile, and various 1,3-dicarbonyl compounds, catalyzed by an amine-functionalized metal-organic framework (MOF) Cu₂(NH₂-BDC)₂(DABCO) as a heterogeneous catalyst with good to excellent yields.

Keywords: 4H-pyrans; Ball milling; Heterogeneous catalyst; Mechanochemical; Metal-organic framework; Solvent-free.