A novel HLA-C06 allele, HLA-C06:02:96, identified by next-generation sequencing in a Chinese family

HLA. 2023 Jul;102(1):95-97. doi: 10.1111/tan.15011. Epub 2023 Mar 8.

Authors

Xiaojing Wang¹, Jiying Wang¹, Yan Zhang¹, Yao Yao¹

Affiliation

¹ Department of Pathology and Lab Medicine, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.

PMID: 36846874
DOI: 10.1111/tan.15011

Abstract

HLA-C*06:02:96 differs from HLA-C*06:02:01:01 (924C → A, I284I), resulting in a synonymous change in exon 5.

Keywords: HLA; new allele; next-generation sequencing.

© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
East Asian People*
Genes, MHC Class I
HLA-C Antigens* / genetics
High-Throughput Nucleotide Sequencing / methods
Humans

Substances

HLA-C Antigens
HLA-C*06 antigen