Association between Long-Term Ambient PM2.5 Exposure and under-5 Mortality: A Scoping Review

Int J Environ Res Public Health. 2023 Feb 13;20(4):3270. doi: 10.3390/ijerph20043270.

Abstract

Studies have established a link between exposure to fine particles (PM2.5) and mortality in infants and children. However, few studies have explored the association between post-birth exposure to PM2.5 and under-5 mortality. We conducted a scoping review to identify relevant epidemiological evidence on the association between post-birth ambient PM2.5 exposure and under-5 mortality. We searched PubMed and Web of Science for articles published between 1970 and the end of January 2022 that explicitly linked ambient PM2.5 and under-5 mortality by considering the study area, study design, exposure window, and child age. Information was extracted on the study characteristics, exposure assessment and duration, outcomes, and effect estimates/findings. Ultimately, 13 studies on infant and child mortality were selected. Only four studies measured the effect of post-birth exposure to PM2.5 on under-5 mortality. Only one cohort study mentioned a positive association between post-birth ambient PM2.5 exposure and under-5 mortality. The results of this scoping review highlight the need for extensive research in this field, given that long-term exposure to ambient PM2.5 is a major global health risk and child mortality remains high in some countries.

Keywords: ambient PM2.5; epidemiological studies; post-birth exposure; review; under-5 mortality.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Air Pollutants* / analysis
  • Air Pollution* / analysis
  • Child
  • Child Mortality
  • Cohort Studies
  • Environmental Exposure
  • Humans
  • Infant
  • Particulate Matter / analysis

Substances

  • Air Pollutants
  • Particulate Matter

Grants and funding

This study is supported by Environment Research and Technology Development Fund S-20 (JPMEERF21S12020) from the Environmental Restoration and Conservation Agency of the Ministry of Environment, Japan.