Covalent Organic Frameworks-Based Electrochemical Sensors for Food Safety Analysis

Biosensors (Basel). 2023 Feb 17;13(2):291. doi: 10.3390/bios13020291.

Abstract

Food safety is a key issue in promoting human health and sustaining life. Food analysis is essential to prevent food components or contaminants causing foodborne-related illnesses to consumers. Electrochemical sensors have become a desirable method for food safety analysis due to their simple, accurate and rapid response. The low sensitivity and poor selectivity of electrochemical sensors working in complex food sample matrices can be overcome by coupling them with covalent organic frameworks (COFs). COFs are a kind of novel porous organic polymer formed by light elements, such as C, H, N and B, via covalent bonds. This review focuses on the recent progress in COF-based electrochemical sensors for food safety analysis. Firstly, the synthesis methods of COFs are summarized. Then, a discussion of the strategies is given to improve the electrochemistry performance of COFs. There follows a summary of the recently developed COF-based electrochemical sensors for the determination of food contaminants, including bisphenols, antibiotics, pesticides, heavy metal ions, fungal toxin and bacterium. Finally, the challenges and the future directions in this field are discussed.

Keywords: antibiotics; covalent organic frameworks; electrochemical sensors; food safety; heavy metal ions; pesticides.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents
  • Food Safety
  • Hazard Analysis and Critical Control Points*
  • Humans
  • Metal-Organic Frameworks*
  • Polymers

Substances

  • Metal-Organic Frameworks
  • Polymers
  • Anti-Bacterial Agents