CT-Guided RFA for Management of Surgical Relapses of Giant Cell Tumour of Bone

Cardiovasc Intervent Radiol. 2023 Apr;46(4):508-511. doi: 10.1007/s00270-023-03382-5. Epub 2023 Feb 23.

Abstract

Objectives: This retrospective study describes a pilot experience in CT-guided RadioFrequency Ablation (RFA) treatment of 5 Giant Cell Tumour of the bone (GCT) recurrences after surgery.

Methods: After biopsy to confirm the diagnosis of GCT recurrences, all patients were treated with RFA in a single session. A close follow-up was scheduled with contrast-enhanced MRI starting 1 months after treatment.

Results: Five lesions were treated in 5 patients. The length of the observation period was between 4 and 100 months. One lesion relapsed 4 months after the RFA treatment, and the patient underwent a second surgical treatment which included the en-block resection and prosthetic implant. No complications were recorded.

Conclusions: The management of GCT relapses with RFA could be an interesting and innovative field. However, the results of this limited series need to be confirmed by further investigations of larger patient cohorts.

Keywords: Bone tumours; Giant cell tumour; Giant cell tumour recurrence; Radiofrequency ablation.

MeSH terms

  • Catheter Ablation* / methods
  • Giant Cell Tumor of Bone* / diagnostic imaging
  • Giant Cell Tumor of Bone* / surgery
  • Humans
  • Recurrence
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome