Antihypertensives in Pregnancy

Obstet Gynecol Clin North Am. 2023 Mar;50(1):39-78. doi: 10.1016/j.ogc.2022.10.008.

Abstract

Hypertensive disorders of pregnancy (HDP) can result in significant maternal morbidity and even mortality. Available data suggest that many antihypertensives can be safely used in pregnant patients, albeit with close supervision of parameters like fetal growth and amniotic fluid volume. This article summarizes current guidelines on the diagnosis and treatment of hypertension in pregnancy and provides an in-depth guide to the available safety and efficacy data for antihypertensives during pregnancy and postpartum.

Keywords: American College of Cardiology; American College of Obstetricians and Gynecologists; American Heart Association; Antihypertensive; Chronic hypertension; Gestational hypertension; Pharmacokinetics in pregnancy; Preeclampsia.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Female
  • Fetal Development
  • Humans
  • Hypertension*
  • Hypertension, Pregnancy-Induced* / diagnosis
  • Postpartum Period
  • Pre-Eclampsia* / diagnosis
  • Pregnancy

Substances

  • Antihypertensive Agents