Pemphigus Vulgaris Possibly Associated with COVID-19 Infection

Yul Hee Kim; Hee Young Kang

doi:10.7759/cureus.33897

Pemphigus Vulgaris Possibly Associated with COVID-19 Infection

Cureus. 2023 Jan 17;15(1):e33897. doi: 10.7759/cureus.33897. eCollection 2023 Jan.

Authors

Yul Hee Kim¹, Hee Young Kang¹

Affiliation

¹ Dermatology, Ajou University School of Medicine, Suwon, KOR.

Abstract

Pemphigus vulgaris (PV) represents damage to epidermal keratinocytes, resulting in acantholysis due to the production of autoantibodies against desmoglein-1 and desmoglein-3. Autoimmune blistering disorders such as pemphigus vulgaris or bullous pemphigoid that develop following coronavirus disease 2019 (COVID-19) have been reported in several studies. Herein, we report a case of PV onset following COVID-19 infection in a 17-year-old female, demonstrating --the potential pathogenic capacity of SARS-CoV-2 to develop PV.

Keywords: autoimmune bullous disease; covid-19; keratinocyte; pemphigus vulgaris; sars-cov-2 spike protein.

Publication types

Case Reports