Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus

Karolina Bełdzińska; Konrad Gądek; Jacek Rutkowski

doi:10.5114/wo.2023.124792

Hypofractionated radiotherapy for renal cell carcinoma with inferior vena cava tumour thrombus

Contemp Oncol (Pozn). 2022;26(4):310-313. doi: 10.5114/wo.2023.124792. Epub 2022 Dec 30.

Authors

Karolina Bełdzińska^{1

2}, Konrad Gądek³, Jacek Rutkowski³

Affiliations

¹ Department of Hematology and Transplantology, University Clinical Centre in Gdansk, Gdansk, Poland.
² Students Scientific Circle of the Department of Oncology and Radiotherapy, Medical University of Gdansk, Gdansk, Poland.
³ Department of Oncology and Radiotherapy, University Clinical Centre in Gdansk, Medical University of Gdansk, Poland.

Abstract

Renal cell carcinoma (RCC) constitutes about 3% of all malignant neoplasms in adults. Clear cell carcinoma is the most frequent type, accounting for about 65% of cases. It tends to invade the veins and form tumour thrombi in inferior vena cava (IVC-TT), occasionally reaching the right atrium. Nephrectomy and thrombectomy are standard therapeutic procedures performed in RCC-IVC-TT. Despite proven effectiveness of surgery, this entity in IVC-TT is associated with poor outcome. The role of palliative radiotherapy in this entity is undetermined. We present a case of a 43-year-old female patient after right-sided nephrectomy due to advanced RCC which invaded the IVC, hepatic veins, and right atrium. The patient has been treated with postoperative, hypofractionated radiotherapy on the residual disease.

Keywords: IVC-TT; case report; hypofractionated radiotherapy; inferior vena cava thrombus; radiation oncology; radiotherapy; renal cancer; renal cell carcinoma.

Publication types

Case Reports