Case report: Primary mediastinal Ewing's sarcoma presenting with chest tightness

Manman Cui; Duchang Zhai; Yan Liu; Xiuzhi Zhou; Tingting Wang; Lihuan Wang; Wu Cai; Guohua Fan; Shenghong Ju

doi:10.3389/fonc.2022.1020339

Case report: Primary mediastinal Ewing's sarcoma presenting with chest tightness

Front Oncol. 2023 Feb 6:12:1020339. doi: 10.3389/fonc.2022.1020339. eCollection 2022.

Authors

Manman Cui¹, Duchang Zhai¹, Yan Liu¹, Xiuzhi Zhou¹, Tingting Wang¹, Lihuan Wang², Wu Cai¹, Guohua Fan¹, Shenghong Ju³

Affiliations

¹ Department of Radiology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
² Department of Radiology, The First People`s Hospital of Taicang, Taicang, China.
³ Department of Radiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China.

Abstract

Ewing's sarcoma is a part of a rare group of malignant neoplasms, whose pathological morphological features are small round cells. Extraskeletal Ewing's sarcoma is a more uncommon primary tumor. Herein, we report the case of a 66-year-old man who complained of chest tightness. Subsequent chest CT scans revealed an irregular and uneven density mass on the right side of the anterior mediastinum with invasion of the superior vena cava, pericardium and right lung. The patient's clinical symptoms were improved after performing excision of the mediastinal lesions under cardiopulmonary bypass. Based on histological and immunohistochemical findings, the tumor was diagnosed as extraskeletal Ewing's sarcoma.

Keywords: Ewing’s sarcoma; chest; extraskeletal; mediastinum; oncology; primary.

Publication types

Case Reports

Grants and funding

This study was supported by the Project of State Key Laboratory of Radiation Medicine and Protection, Soochow University (GZK1202136), “National Tutor System” Training Program for Health Youth Key Talents in Suzhou (Qngg2021006、Qngg2021039), Suzhou Health Talent (GSWS2021025), “Image Medical Star” Project of Suzhou Medical Association (2022YX-M05), Pre-research Foundation of Second Affiliated Hospital of Soochow University (SDFEYBS1904), and Project of Nuclear Technology Medical Application Supported by Discipline Construction of Second Affiliated Hospital of Soochow University (XKTJ-HRC20210010). The authors declare that this study received funding from “Technological Innovation” Project of CNNC Medical Industry Co. Ltd. (ZHYLYB2021006). The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of the article, or the decision to submit it for publication.