Advances in the oral microbiota and rapid detection of oral infectious diseases

Xuan Xiao; Shangfeng Liu; Hua Deng; Yuhan Song; Liang Zhang; Zhifeng Song

doi:10.3389/fmicb.2023.1121737

Advances in the oral microbiota and rapid detection of oral infectious diseases

Front Microbiol. 2023 Feb 6:14:1121737. doi: 10.3389/fmicb.2023.1121737. eCollection 2023.

Authors

Xuan Xiao^{1

2}, Shangfeng Liu², Hua Deng³, Yuhan Song^{1

2}, Liang Zhang³, Zhifeng Song^{1

2}

Affiliations

¹ Department of Oral Mucosa, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
² Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
³ Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, China.

Abstract

Several studies have shown that the dysregulation of the oral microbiota plays a crucial role in human health conditions, such as dental caries, periodontal disease, oral cancer, other oral infectious diseases, cardiovascular diseases, diabetes, bacteremia, and low birth weight. The use of traditional detection methods in conjunction with rapidly advancing molecular techniques in the diagnosis of harmful oral microorganisms has expanded our understanding of the diversity, location, and function of the microbiota associated with health and disease. This review aimed to highlight the latest knowledge in this field, including microbial colonization; the most modern detection methods; and interactions in disease progression. The next decade may achieve the rapid diagnosis and precise treatment of harmful oral microorganisms.

Keywords: infectious diseases; microbiota; oral cavity; precise treatment; rapid diagnosis.

Publication types

Review