Paper-based analytical device coupled with Bi-MOF: Electric field amplification and fluorescence sensing of glyphosate

Chao-Qun Wan; Yue-Hong Pang; Qiu-Yu Yang; Cheng-Lin Yang; Xiao-Fang Shen

doi:10.1016/j.aca.2023.340930

Paper-based analytical device coupled with Bi-MOF: Electric field amplification and fluorescence sensing of glyphosate

Anal Chim Acta. 2023 Apr 1:1248:340930. doi: 10.1016/j.aca.2023.340930. Epub 2023 Feb 1.

Authors

Chao-Qun Wan¹, Yue-Hong Pang¹, Qiu-Yu Yang¹, Cheng-Lin Yang¹, Xiao-Fang Shen²

Affiliations

¹ State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, Wuxi, 214122, China.
² State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, Wuxi, 214122, China. Electronic address: xfshen@jiangnan.edu.cn.

PMID: 36813460
DOI: 10.1016/j.aca.2023.340930

Abstract

Glyphosate, a potent herbicide wildly used in the world, involves potential hazards to human health by accumulating in the food chain. Due to its absence of chromophores and fluorophores, the rapid visual detection of glyphosate has always been difficult. Herein, a paper-based geometric field amplification device visualized by the amino-functionalized bismuth-based metal-organic framework (NH₂-Bi-MOF) was constructed for sensitive fluorescence determination of glyphosate. Fluorescence of the synthesized NH₂-Bi-MOF was immediately enhanced by interaction with glyphosate. The field amplification of glyphosate was implemented by coordinating the electric field and the electroosmotic flow, which was orchestrated by the geometric configuration of paper channel and the concentration of polyvinyl pyrrolidone, respectively. Under the optimal conditions, the developed method exhibited a linear range of 0.80-200 μmol L^-1 with about 12500-fold signal enhancement achieved by just 100 s electric field amplification. It was applied to soil and water with recoveries between 95.7% and 105.6%, holding great prospects in on-site analysis of hazardous anions for environment safety.

Keywords: Electric field amplification; Fluorescence; Glyphosate; Metal-organic framework; PAD.