Groundwater fluoride and nitrate contamination and associated human health risk assessment in South Punjab, Pakistan

Abstract

Consumption of high fluoride (F^-) and nitrate (NO₃^-) containing water may pose serious health hazards. One hundred sixty-one groundwater samples were collected from drinking wells in Khushab district, Punjab Province, Pakistan, to determine the causes of elevated F^- and NO₃^- concentrations, and to estimate the human health risks posed by groundwater contamination. The results showed pH of the groundwater samples ranged from slightly neutral to alkaline, and Na⁺ and HCO₃^- ions dominated the groundwater. Piper diagram and bivariate plots indicated that the key factors regulating groundwater hydrochemistry were weathering of silicates, dissolution of evaporates, evaporation, cation exchange, and anthropogenic activities. The F^- content of groundwater ranged from 0.06 to 7.9 mg/L, and 25.46% of groundwater samples contained high-level fluoride concentration (F^- > 1.5 mg/L), which exceeds the (WHO Guidelines for drinking-water quality: incorporating the first and second addenda, WHO, Geneva, 2022) guidelines of drinking-water quality. Inverse geochemical modeling indicates that weathering and dissolution of fluoride-rich minerals were the primary causes of F^- in groundwater. High F^- can be attributed to low concentration of calcium-containing minerals along the flow path. The concentrations of NO₃^- in groundwater varied from 0.1 to 70 mg/L; some samples are slightly exceeding the (WHO Guidelines for drinking-water quality: incorporating the first and second addenda, WHO, Geneva, 2022) guidelines for drinking-water quality. Elevated NO₃^- content was attributed to the anthropogenic activities revealed by PCA analysis. The high levels of nitrates found in the study region are a result of various human-caused factors, including leaks from septic systems, the use of nitrogen-rich fertilizers, and waste from households, farming operations, and livestock. The hazard quotient (HQ) and total hazard index (THI) of F^- and NO₃^- showed high non-carcinogenic risk (> 1) via groundwater consumption, demonstrating a high potential risk to the local population. This study is significant because it is the most comprehensive examination of water quality, groundwater hydrogeochemistry, and health risk assessment in the Khushab district to date, and it will serve as a baseline for future studies. Some sustainable measures are urgent to reduce the F^- and NO₃^- content in the groundwater.

Keywords: Fluoride; Groundwater quality; Nitrate; Water–rock interaction.