Effects of Electrical Stimulation of the Cell: Wound Healing, Cell Proliferation, Apoptosis, and Signal Transduction

Kazuo Katoh

doi:10.3390/medsci11010011

Effects of Electrical Stimulation of the Cell: Wound Healing, Cell Proliferation, Apoptosis, and Signal Transduction

Med Sci (Basel). 2023 Jan 17;11(1):11. doi: 10.3390/medsci11010011.

Author

Kazuo Katoh¹

Affiliation

¹ Laboratory of Human Anatomy and Cell Biology, Faculty of Health Sciences, Tsukuba University of Technology, Tsukuba 305-8521, Japan.

Abstract

Electrical stimulation of the cell can have a number of different effects depending on the type of cell being stimulated. In general, electrical stimulation can cause the cell to become more active, increase its metabolism, and change its gene expression. For example, if the electrical stimulation is of low intensity and short duration, it may simply cause the cell to depolarize. However, if the electrical stimulation is of high intensity or long duration, it may cause the cell to become hyperpolarized. The electrical stimulation of cells is a process by which an electrical current is applied to cells in order to change their function or behavior. This process can be used to treat various medical conditions and has been shown to be effective in a number of studies. In this perspective, the effects of electrical stimulation on the cell are summarized.

Keywords: cell adhesion; cultured cells; cytoskeleton; electrical stimulation; signal transduction.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Apoptosis
Cell Proliferation
Electric Stimulation
Signal Transduction*
Wound Healing* / physiology

Grants and funding

The work reported here was supported by Grants-in-Aid for Promotional Projects for Advanced Education and Research, National University Cooperation, Tsukuba University of Technology. The funders had no role in the study design, data collection, analysis, decision to publish, or preparation of the manuscript.