Till SMARCA5 loss do nucleosomes part

Mol Cell. 2023 Feb 16;83(4):500-501. doi: 10.1016/j.molcel.2023.01.022.

Abstract

In this issue of Molecular Cell, Bomber et al. demonstrate that acute loss of SMARCA5 in human cells leads to eviction of CTCF and an increase in nucleosome repeat length without direct impact on transcriptional activity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Adenosine Triphosphatases*
  • Chromosomal Proteins, Non-Histone / genetics
  • Humans
  • Nucleosomes* / genetics

Substances

  • Nucleosomes
  • SMARCA5 protein, human
  • Adenosine Triphosphatases
  • Chromosomal Proteins, Non-Histone