Converting and hoarding driven by protein phosphorylation in Toxoplasma gondii

Trends Parasitol. 2023 Apr;39(4):232-234. doi: 10.1016/j.pt.2023.02.002. Epub 2023 Feb 17.

Abstract

Successful parasitism relies on the evasion of adversarial host responses. Wang et al. have recently shown that Toxoplasma gondii relies on the protein phosphatase 2A (PP2A) to cause persisting infections. The phosphatase controls the development of dormant parasite stages and the accumulation of sugar supplies.

Keywords: Toxoplasma gondii; bradyzoites; metabolism; protein phosphatase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Hoarding*
  • Phosphorylation
  • Protein Processing, Post-Translational
  • Toxoplasma* / physiology