miRNA as Drug: Antagomir and Beyond

Curr Pharm Des. 2023;29(6):462-465. doi: 10.2174/1381612829666230220123150.

Abstract

MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 20 to 25 nucleotides, present in all body fluids; they can be used as biomarkers, but much more than this as a therapy to replace missing protein or to downregulate excess or aberrant synthesis; here we report possible insight to future studies, needed in this exciting field.

Keywords: MicroRNA; agomir; antagomir; exosomes; miRNA-sponge; non-coding RNA.

MeSH terms

  • Antagomirs
  • Humans
  • MicroRNAs* / genetics
  • MicroRNAs* / metabolism
  • Proteins

Substances

  • MicroRNAs
  • Antagomirs
  • Proteins