Antibacterial Carbon Dots-Based Composites

Small. 2023 Aug;19(31):e2207385. doi: 10.1002/smll.202207385. Epub 2023 Feb 17.

Abstract

The emergence and global spread of bacterial resistance to conventionally used antibiotics have highlighted the urgent need for new antimicrobial agents that might replace antibiotics. Currently, nanomaterials hold considerable promise as antimicrobial agents in anti-inflammatory therapy. Due to their distinctive functional physicochemical characteristics and exceptional biocompatibility, carbon dots (CDs)-based composites have attracted a lot of attention in the context of these antimicrobial nanomaterials. Here, a thorough assessment of current developments in the field of antimicrobial CDs-based composites is provided, starting with a brief explanation of the general synthesis procedures, categorization, and physicochemical characteristics of CDs-based composites. The many processes driving the antibacterial action of these composites are then thoroughly described, including physical destruction, oxidative stress, and the incorporation of antimicrobial agents. Finally, the obstacles that CDs-based composites now suffer in combating infectious diseases are outlined and investigated, along with the potential applications of antimicrobial CDs-based composites.

Keywords: antibacterial; carbon dots; carbon dots-based composites; membrane disruption; oxidative stress.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Infective Agents*
  • Carbon
  • Nanostructures*
  • Quantum Dots*

Substances

  • Carbon
  • Anti-Bacterial Agents
  • Anti-Infective Agents