Objective: To review the research progress of digital occlusion setup in orthognathic surgery.
Methods: The literature related to digital occlusion setup in orthognathic surgery in recent years was consulted, and the imaging basis, methods, clinical applications as well as existing problems were reviewed.
Results: Digital occlusion setup in orthognathic surgery includes manual, semi-automatics, and fully automatic methods. The manual method mainly relies on visual cues for operation, which is difficult to ensure the best occlusion set up, though relatively flexible. The semi-automatic method utilizes the computer software for partial occlusion set up and adjustment, but the occlusion result is still largely depended by manual operation. The fully automatic method completely depends on the operation of computer software, and targeted algorithms for different occlusion reconstruction situations are needed.
Conclusion: The preliminary research results have confirmed the accuracy and reliability of digital occlusion setup in orthognathic surgery, but there are still some limitations. Further research is needed in terms of postoperative outcomes, doctor and patient acceptance, planning time and cost-effectiveness.
目的: 对正颌外科数字化咬合设置的研究进展进行综述。.
方法: 查阅近年来与正颌外科数字化咬合设置相关的研究文献，对其成像基础、方法、临床应用以及存在问题进行总结和梳理。.
结果: 正颌外科数字化咬合设置包括手动、半自动和全自动方法。手动方法主要依赖视觉线索进行操作，相对灵活，但难以保证最佳咬合设置；半自动方法利用计算机软件自动运行部分咬合设置和调整，但咬合结果很大程度上仍取决于人为操作；全自动方法完全依赖于计算机软件的运行，对不同临床情况需要设计针对性的咬合重建算法。.
结论: 目前的临床研究初步证实了正颌外科数字化咬合设置的准确性和可靠性，但仍存在一定局限性，未来还需要在术后结果、医患接受度、规划时间和成本效益等方面展开进一步研究。.
Keywords: Dental occlusion; computer simulation; dental model; orthognathic surgery; three-dimensional imaging.