Favorable pharmacokinetic and pharmacodynamic properties of gilteritinib in cerebrospinal fluid: a potential effective treatment in relapsing meningeal acute myeloid leukemia FLT3-ITD patients

Haematologica. 2023 Sep 1;108(9):2531-2534. doi: 10.3324/haematol.2022.282596.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aniline Compounds* / cerebrospinal fluid
  • Aniline Compounds* / pharmacokinetics
  • Aniline Compounds* / pharmacology
  • Aniline Compounds* / therapeutic use
  • Humans
  • Leukemia, Myeloid, Acute* / drug therapy
  • Mutation
  • Pyrazines / pharmacology
  • Treatment Outcome
  • fms-Like Tyrosine Kinase 3 / genetics

Substances

  • Aniline Compounds
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3
  • gilteritinib
  • Pyrazines