Structure elucidation of an aspidofractinine-type monoterpene indole alkaloid from Melodinus reticulatus

Abstract

The structure and complete NMR assignments of aspidoreticulofractine, an aspidofractinine N-oxide, are reported. Its structure was elucidated based on a combination of spectroscopic techniques including 1D and 2D NMR, high-resolution mass spectrometry, and electronic circular dichroism.

Keywords: Melodinus reticulatus; apocynaceae; aspidofractane; monoterpene indole alkaloid; structure elucidation.