Joint learning-based causal relation extraction from biomedical literature

J Biomed Inform. 2023 Mar:139:104318. doi: 10.1016/j.jbi.2023.104318. Epub 2023 Feb 11.

Abstract

Causal relation extraction of biomedical entities is one of the most complex tasks in biomedical text mining, which involves two kinds of information: entity relations and entity functions. One feasible approach is to take relation extraction and function detection as two independent sub-tasks. However, this separate learning method ignores the intrinsic correlation between them and leads to unsatisfactory performance. In this paper, we propose a joint learning model, which combines entity relation extraction and entity function detection to exploit their commonality and capture their inter-relationship, so as to improve the performance of biomedical causal relation extraction. Experimental results on the BioCreative-V Track 4 corpus show that our joint learning model outperforms the separate models in BEL statement extraction, achieving the F1 scores of 57.0% and 37.3% on the test set in Stage 2 and Stage 1 evaluations, respectively. This demonstrates that our joint learning system reaches the state-of-the-art performance in Stage 2 compared with other systems.

Keywords: BEL Statement; Function Detection; Joint Learning; Relation Extraction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Data Mining* / methods
  • Knowledge Discovery
  • Machine Learning*