A Retrospective Study to Evaluate the Role of Dynamic Fracture Mobility in the Conservative Treatment of Osteoporotic Vertebral Compression Fractures

World Neurosurg. 2023 May:173:e189-e193. doi: 10.1016/j.wneu.2023.02.031. Epub 2023 Feb 11.

Abstract

Objective: To investigate whether dynamic fracture mobility could affect the outcome of conservative treatment in patients with acute osteoporotic vertebral compression fracture (OVCF).

Methods: A total of 158 patients who underwent conservative treatment in our hospital for painful OVCFs were included in this study and their data were retrospectively analyzed. According to the degree of pain relief, patients were divided into an excellent efficacy group and a poor efficacy group. Factors that may affect the outcome of conservative treatment were recorded for each patient. Variables with a statistical difference between the 2 groups were entered into multivariate logistic regression analysis to identify the factors influencing the outcome of conservative treatment. Receiver operating characteristic curve analysis was also performed.

Results: The result showed that dynamic fracture mobility, overweight, age, and bone mineral density (BMD) (all P < 0.001) were independent factors influencing the outcome of conservative treatment. Receiver operating characteristic curve analysis showed that the cutoff values for age and BMD that predicted treatment effect were 72.5 years and -3.30, respectively.

Conclusions: This study confirmed that dynamic fracture mobility could be used as an independent factor predicting the outcome of conservative treatment in patients with acute OVCFs. It was also shown that overweight, age, and BMD were other independent factors influencing the outcome of conservative treatment. A comprehensive evaluation of these related factors can guide the doctor to take appropriate treatment for a unique acute OCVF.

Keywords: Conservative treatment; Dynamic fracture mobility; Osteoporotic vertebral compression fracture.

MeSH terms

  • Conservative Treatment
  • Fractures, Compression* / etiology
  • Fractures, Compression* / surgery
  • Humans
  • Kyphoplasty* / adverse effects
  • Osteoporotic Fractures* / etiology
  • Osteoporotic Fractures* / surgery
  • Overweight
  • Retrospective Studies
  • Spinal Fractures* / complications
  • Spinal Fractures* / surgery
  • Treatment Outcome
  • Vertebroplasty* / adverse effects