A large-scale organoid-based screening platform to advance drug repurposing in pancreatic cancer

Cell Genom. 2022 Feb 9;2(2):100100. doi: 10.1016/j.xgen.2022.100100.

Abstract

Hirt et al.1 report an automated, high-throughput drug screening platform for organoid cultures to enable repurposing of previously approved drugs for pancreatic cancers harboring specific genetic alterations. The pancreatic cancer organoid biobank also represents a valuable tool to uncover new drug-gene interactions in pancreatic tumors.

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  • News