Transmission Dynamics and Epidemiological Characteristics of the SARS-CoV-2 Delta Variant - Hunan Province, China, 2021

China CDC Wkly. 2023 Jan 20;5(3):56-62. doi: 10.46234/ccdcw2023.011.

Abstract

What is already known about this topic?: Little is known about the epidemiology, natural history, and transmission patterns of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant. Monitoring the evolution of viral fitness of SARS-CoV-2 in the host population is key for preparedness and response planning.

What is added by this report?: We analyzed a successfully contained local outbreak of Delta that took place in Hunan, China, and provided estimates of time-to-key event periods, infectiousness over time, and risk factors for SARS-CoV-2 infection and transmission for a still poorly understood variant.

What are the implications for public health practice?: Our findings simultaneously shed light on both the characteristics of the Delta variant, by identifying key age groups, risk factors, and transmission pathways, and planning a future response effort against SARS-CoV-2.

Keywords: Delta variant; Transmission dynamics; epidemiological characteristics.

Grants and funding

Supported by grants from the Key Program of the National Natural Science Foundation of China (82130093), Shanghai Municipal Science and Technology Major Project (ZD2021CY001), Hunan Provincial Innovative Construction Special Fund: Emergency response to COVID-19 outbreak (No. 2020SK3012), and Chinese Academy of Medical Sciences Coronavirus Disease 2019 Science and Technology Research Project in 2020 (No. 2020HY320003)