Delta Variant: Partially Sensitive To Vaccination, but Still Worth Global Attention

J Transl Int Med. 2022 Sep 24;10(3):227-235. doi: 10.2478/jtim-2022-0026. eCollection 2022 Sep.

Abstract

The pandemic coronavirus disease 2019 (COVID-19) has rapidly spread to all countries worldwide. The emergence of its variants has exacerbated this problem. To date, many variants have been identified across the viral genome; the variants of concern are the focus of attention due to their higher transmissibility and resistance to vaccines, especially the delta variant. The delta variant has become the dominant severe acute respiratory syndrome novel coronavirus (SARS-CoV-2) variant worldwide, causing severe panic as it is highly infectious. A better understanding of these variants may help in the development of possible treatments and save more lives. In this study, we summarize the characteristics of the variants of concern. More importantly, we summarize the results of previous studies on the delta variant. The delta variant has a high transmissibility rate and increases the risk of hospitalization and death. However, it is partially sensitive to vaccines. In addition, nonpharmaceutical interventions are valuable during epidemics. These interventions can be used against the delta variant, but managing this variant should still be taken seriously.

Keywords: delta variant; severe acute respiratory syndrome novel coronavirus; vaccine; variants of concern.

Grants and funding

This study was supported by the Specialized Department Foundation of the Minhang District (No.2020 MWTZB02) and Shanghai Municipal Science and Technology Commission (No. 20ZR1443700).