Porous Framework Materials for Bioimaging and Cancer Therapy

Molecules. 2023 Jan 31;28(3):1360. doi: 10.3390/molecules28031360.

Abstract

Cancer remains one of the most pressing diseases in the world. Traditional treatments, including surgery, chemotherapy, and radiotherapy still show certain limitations. Recently, numerous cancer treatments have been proposed in combination with novel materials, such as photothermal therapy, chemodynamic therapy, immunotherapy, and a combination of therapeutic approaches. These new methods have shown significant advantages in reducing side effects and synergistically enhancing anti-cancer efficacy. In addition to the above approaches, early diagnosis and in situ monitoring of lesion areas are also important for reducing side effects and improving the success rate of cancer therapy. This depends on the decent use of bioimaging technology. In this review, we mainly summarize the recent advances in porous framework materials for bioimaging and cancer therapy. In addition, we present future challenges relating to bioimaging and cancer therapy based on porous framework materials.

Keywords: bioimaging; cancer; chemodynamic therapy; photodynamic therapy; photothermal therapy; porous framework materials.

Publication types

  • Review

MeSH terms

  • Combined Modality Therapy
  • Humans
  • Neoplasms* / diagnostic imaging
  • Neoplasms* / therapy
  • Photochemotherapy*
  • Phototherapy
  • Porosity