Automatic Detection of Oral Squamous Cell Carcinoma from Histopathological Images of Oral Mucosa Using Deep Convolutional Neural Network

Int J Environ Res Public Health. 2023 Jan 24;20(3):2131. doi: 10.3390/ijerph20032131.

Abstract

Worldwide, oral cancer is the sixth most common type of cancer. India is in 2nd position, with the highest number of oral cancer patients. To the population of oral cancer patients, India contributes to almost one-third of the total count. Among several types of oral cancer, the most common and dominant one is oral squamous cell carcinoma (OSCC). The major reason for oral cancer is tobacco consumption, excessive alcohol consumption, unhygienic mouth condition, betel quid eating, viral infection (namely human papillomavirus), etc. The early detection of oral cancer type OSCC, in its preliminary stage, gives more chances for better treatment and proper therapy. In this paper, author proposes a convolutional neural network model, for the automatic and early detection of OSCC, and for experimental purposes, histopathological oral cancer images are considered. The proposed model is compared and analyzed with state-of-the-art deep learning models like VGG16, VGG19, Alexnet, ResNet50, ResNet101, Mobile Net and Inception Net. The proposed model achieved a cross-validation accuracy of 97.82%, which indicates the suitability of the proposed approach for the automatic classification of oral cancer data.

Keywords: deep convolutional neural network; histopathological images; oral cancer.

MeSH terms

  • Carcinoma, Squamous Cell* / epidemiology
  • Head and Neck Neoplasms*
  • Humans
  • Mouth Mucosa
  • Mouth Neoplasms* / epidemiology
  • Neural Networks, Computer
  • Squamous Cell Carcinoma of Head and Neck

Grants and funding

This research received no external funding.