ViralVacDB: A manually curated repository of viral vaccines

Sadhana Tripathi; Neelam Sharma; Leimarembi Devi Naorem; Gajendra P S Raghava

doi:10.1016/j.drudis.2023.103523

ViralVacDB: A manually curated repository of viral vaccines

Drug Discov Today. 2023 Apr;28(4):103523. doi: 10.1016/j.drudis.2023.103523. Epub 2023 Feb 9.

Authors

Sadhana Tripathi¹, Neelam Sharma², Leimarembi Devi Naorem³, Gajendra P S Raghava⁴

Affiliations

¹ Department of Computational Biology, Indraprastha Institute of Information Technology, Okhla Phase 3, New Delhi 110020, India. Electronic address: sadhana20214@iiitd.ac.in.
² Department of Computational Biology, Indraprastha Institute of Information Technology, Okhla Phase 3, New Delhi 110020, India. Electronic address: neelams@iiitd.ac.in.
³ Department of Computational Biology, Indraprastha Institute of Information Technology, Okhla Phase 3, New Delhi 110020, India. Electronic address: leimarembi@gmail.com.
⁴ Department of Computational Biology, Indraprastha Institute of Information Technology, Okhla Phase 3, New Delhi 110020, India. Electronic address: raghava@iiitd.ac.in.

PMID: 36764575
DOI: 10.1016/j.drudis.2023.103523

Abstract

Over the years, numerous vaccines have been developed against viral infections; however, a complete database that provides comprehensive information on viral vaccines has been lacking. In this review, along with our freely accessible database ViralVacDB, we provide details of the viral vaccines, their type, routes of administration and approving agencies. This repository systematically covers additional information such as disease name, adjuvant, manufacturer, clinical status, age and dosage against 422 viral vaccines, including 145 approved vaccines and 277 in clinical trials. We anticipate that this database will be highly beneficial to researchers and others working in pharmaceuticals and immuno-informatics.

Keywords: approved vaccines; clinical trials; database; vaccines; viral diseases; virus.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Databases, Factual
Humans
Viral Vaccines*
Virus Diseases* / prevention & control

Substances

Viral Vaccines