Regenerative Endodontic Management of an Immature Necrotic Premolar Using Advanced Platelet-Rich Fibrin

Sepideh Hosseini; Nazanin Chitsaz; Mohammad Hassan Hamrah; Donya Maleki; Emad Taghizadeh

doi:10.1155/2023/1135413

Regenerative Endodontic Management of an Immature Necrotic Premolar Using Advanced Platelet-Rich Fibrin

Case Rep Dent. 2023 Jan 31:2023:1135413. doi: 10.1155/2023/1135413. eCollection 2023.

Authors

Sepideh Hosseini¹, Nazanin Chitsaz², Mohammad Hassan Hamrah³, Donya Maleki⁴, Emad Taghizadeh⁵

Affiliations

¹ Department of Pediatric Dentistry, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
² Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
³ Department of Public Health and Health Systems, Nagoya University Graduate School of Medicine, Nagoya, Japan.
⁴ Faculty of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
⁵ Department of Oral and Maxillofacial Surgery, School of Dentistry, Guilan University of Medical Sciences, Iran.

Abstract

Regenerative endodontic management is a feasible treatment for immature teeth with periapical radiolucency and necrotic pulp that simplifies continued root creation. Among the most prevalent health problems in an immature root is dental pulp necrosis, which is caused by caries, improper endodontic treatments, and trauma. Necrosis of the dental pulp can affect long-term tooth survival and preservation and serve as a source of bacteria infecting the periapical tissue and the maxillofacial space. Here, we report on the application of advanced platelet-rich fibrin plus (A-PRF+) therapy, as a regenerative endodontic treatment (RET), in a 12-year-old with necrotic pulp and asymptomatic apical periodontitis. Over a 24-month follow-up post-treatment, we observed resolving of symptoms and a complete root formation with considerable periapical healing.

Publication types

Case Reports