1 Department of Laboratory Medicine, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
2 Department of Hematology/Oncology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
3 Cancer and Blood Disease Institute, Department of Pediatrics, Children's Hospital Los Angeles and Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
4 Department of Pathology, Children's Hospital Los Angeles and Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
5 Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan.
6 Center for Advanced Medical Engineering Research and Development, Kobe University, Kobe, Japan.
Keywords:
cancer genetics; central nervous system (CNS) tumors; children and adolescent; clinical trials; developmental therapeutics; molecular biology; risk-based approach.