Stereolithography apparatus and digital light processing-based 3D bioprinting for tissue fabrication

Wanlu Li; Mian Wang; Huiling Ma; Fabiola A Chapa-Villarreal; Anderson Oliveira Lobo; Yu Shrike Zhang

doi:10.1016/j.isci.2023.106039

Stereolithography apparatus and digital light processing-based 3D bioprinting for tissue fabrication

iScience. 2023 Jan 24;26(2):106039. doi: 10.1016/j.isci.2023.106039. eCollection 2023 Feb 17.

Authors

Wanlu Li¹, Mian Wang¹, Huiling Ma¹, Fabiola A Chapa-Villarreal¹, Anderson Oliveira Lobo², Yu Shrike Zhang¹

Affiliations

¹ Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.
² Interdisciplinary Laboratory for Advanced Materials (LIMAV), Materials Science and Engineering Graduate Program (PPGCM), Federal University of Piauí (UFPI), Teresina, PI 64049-550, Brazil.

Abstract

Three-dimensional (3D) bioprinting has emerged as a class of promising techniques in biomedical research for a wide range of related applications. Specifically, stereolithography apparatus (SLA) and digital light processing (DLP)-based vat-polymerization techniques are highly effective methods of bioprinting, which can be used to produce high-resolution and architecturally sophisticated structures. Our review aims to provide an overview of SLA- and DLP-based 3D bioprinting strategies, starting from factors that affect these bioprinting processes. In addition, we summarize the advances in bioinks used in SLA and DLP, including naturally derived and synthetic bioinks. Finally, the biomedical applications of both SLA- and DLP-based bioprinting are discussed, primarily centered on regenerative medicine and tissue modeling engineering.

Keywords: Bioengineering; Biotechnology; Materials chemistry; Materials science; Tissue Engineering.

Publication types

Review