Potential application of probiotics in mycotoxicosis reduction in mammals and poultry

Crit Rev Toxicol. 2022 Oct;52(9):731-741. doi: 10.1080/10408444.2023.2168176. Epub 2023 Feb 9.

Abstract

Mycotoxins in feedstuffs are considered as a principal worry by food safety authorities worldwide because most of them can be transferred from the feed to food commodities of animal origin, and further consumed by humans. Therefore, effective alternatives for the reduction of the impact of mycotoxins need to be applied in the feed production industry. Applications of beneficial microorganisms (probiotics) can be alternative and applied as feed additives in order to reduce or eliminate the toxic effects of mycotoxins on animals. The aim of this article is to provide information on the role of beneficial microorganisms (probiotics) and point out their role in the reduction of the effect of mycotoxin toxicity in farming animals (mammals and poultry). The objective was to provide a summary of the existing knowledge based on the application of different strains belonging to the group of lactic acid bacteria (LAB) or yeasts that are already or can be future employed in the feed industry, in order to reduce mycotoxicosis presence in mammals and poultry exposed to mycotoxin-contaminated feed. Moreover, an overview of mycotoxins toxicity in mammals and poultry will be presented, and furthermore, the role of the beneficial microorganisms (including probiotics) in the reduction of mycotoxins toxicity (aflatoxicosis, deoxynivalenol, zearalenone, ochratoxin A, and fumonisin toxicities) will be described in detail.

Keywords: Lactic acid bacteria; in vivo; mycotoxin; toxicity; yeast.

Publication types

  • Review

MeSH terms

  • Animals
  • Food Contamination
  • Humans
  • Mammals
  • Mycotoxicosis*
  • Mycotoxins* / toxicity
  • Poultry
  • Probiotics*

Substances

  • Mycotoxins