Associations between sugar-sweetened beverages before and during pregnancy and offspring overweight/obesity in Japanese women: the TMM BirThree Cohort Study

Public Health Nutr. 2023 Jun;26(6):1222-1229. doi: 10.1017/S1368980023000307. Epub 2023 Feb 9.

Abstract

Objective: The association between high sugar-sweetened beverages (SSB) intake during pregnancy and offspring overweight/obesity has been reported only from Western countries. The objective of this study was to examine the association between SSB intake before and during pregnancy and offspring overweight/obesity among Japanese women.

Design: Japanese prospective birth cohort study.

Setting: We analysed mother-offspring pairs who participated in the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study from 2013 to 2017. SSB intake during pregnancy was evaluated using the FFQ and classified into three groups: none (0 g/d), medium (<195 g/d) and high (>195 g/d). Overweight or obesity at 1 year of age in offspring was defined as having a BMI Z-score greater than 2 sd, calculated based on the BMI reference data for Japanese children. Multiple logistic regression analyses were performed to examine the associations between SSB intake before and during pregnancy and offspring overweight/obesity, after adjusting for covariates.

Participants: Japanese mother-offspring pairs (n 7114).

Results: The overweight/obesity rate of the offspring was 8·8 %. Pregnant women with a high intake of SSB in early to mid-pregnancy had a higher risk of overweight/obesity in their offspring compared with those who did not; the OR was 1·52 (95 % CI (1·09, 2·12)).

Conclusions: High SSB intake in early to mid-pregnancy was associated with an increased risk of offspring overweight/obesity at 1 year of age.

Keywords: Japan; Offspring overweight/obesity; Pregnancy; Sugar-sweetened beverages.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • East Asian People
  • Female
  • Humans
  • Obesity* / epidemiology
  • Obesity* / etiology
  • Overweight* / complications
  • Overweight* / etiology
  • Pregnancy
  • Prospective Studies
  • Sugar-Sweetened Beverages* / adverse effects