Nanomaterials for fluorescent assay of bilirubin

Yongming Guo; Chengwei Wei; Ruiqing Wang; Yubin Xiang

doi:10.1016/j.ab.2023.115078

Nanomaterials for fluorescent assay of bilirubin

Anal Biochem. 2023 Apr 1:666:115078. doi: 10.1016/j.ab.2023.115078. Epub 2023 Feb 7.

Authors

Yongming Guo¹, Chengwei Wei², Ruiqing Wang², Yubin Xiang³

Affiliations

¹ School of Chemistry and Materials Science, Nanjing University of Information Science & Technology, Nanjing, 210044, China. Electronic address: yongmingguo@nuist.edu.cn.
² School of Chemistry and Materials Science, Nanjing University of Information Science & Technology, Nanjing, 210044, China.
³ School of Chemistry and Materials Science, Nanjing University of Information Science & Technology, Nanjing, 210044, China. Electronic address: yubinxiang@nuist.edu.cn.

PMID: 36754137
DOI: 10.1016/j.ab.2023.115078

Abstract

The accumulation of bilirubin in blood is associated with many diseases. Sensitive and accurate detection of bilirubin is of great significance for personal health care. The rapid development of fluorescent nanomaterials promotes rapid development in the bilirubin assay. In this review, traditional methods for detection of bilirubin are briefly presented to compare with fluorescent nanosensors. Subsequently, the recent progress of different types of fluorescent nanomaterials for determination of bilirubin is summarized. Further, the performance of fluorescent nanosensors and conventional techniques for sensing bilirubin are compared. To this end, the challenges and prospects concerning the topics are discussed. This review will provide some introductory knowledge for researchers to understand the status and importance of fluorescent nanosensors for sensing bilirubin.

Keywords: Bilirubin; Detection; Fluorescence; Nanomaterials; Review.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Bilirubin*
Coloring Agents
Nanostructures*

Substances

Bilirubin
Coloring Agents