Insulin-like growth factor 1: A new prime mover in the pathogenesis of vitiligo

Australas J Dermatol. 2023 May;64(2):e188-e191. doi: 10.1111/ajd.13999. Epub 2023 Feb 8.

Authors

Mohammed Hussein Medhat El-Komy¹, Khadiga S Sayed¹, Wedad Z Mostafa¹, Olfat Shaker², Nada Nasser³, Mohammed Hassan³

Affiliations

¹ Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
² Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
³ Dermatology Department, Faculty of Medicine, Fayoum University, Cairo, Egypt.

PMID: 36752172
DOI: 10.1111/ajd.13999

No abstract available

Keywords: hydrogen peroxide (H2O2); insulin-like growth factor-1; melanocyte; reactive oxygen species (ROS).

Publication types

Letter

MeSH terms

Humans
Hypopigmentation* / pathology
Insulin-Like Growth Factor I / metabolism
Melanocytes / pathology
Reactive Oxygen Species / metabolism
Vitiligo* / pathology

Substances

Insulin-Like Growth Factor I
Reactive Oxygen Species
IGF1 protein, human