Critical illness-related cardiac arrest: Protocol for an investigation of the incidence and outcome of cardiac arrest within intensive care units in the United Kingdom

Robert Darnell; Christopher Newell; Julia Edwards; Emma Gendall; David Harrison; Stefan Sprinckmoller; Paul Mouncey; Doug Gould; Matt Thomas

doi:10.1177/17511437211055899

Critical illness-related cardiac arrest: Protocol for an investigation of the incidence and outcome of cardiac arrest within intensive care units in the United Kingdom

J Intensive Care Soc. 2022 Nov;23(4):493-497. doi: 10.1177/17511437211055899. Epub 2022 Mar 13.

Authors

Robert Darnell¹, Christopher Newell², Julia Edwards¹, Emma Gendall³, David Harrison¹, Stefan Sprinckmoller¹, Paul Mouncey¹, Doug Gould¹, Matt Thomas²

Affiliations

¹ Clinical Trials Unit, Intensive Care National Audit & Research Centre (ICNARC), London, UK.
² Department of Anaesthesia, Southmead Hospital, Bristol, UK.
³ Clinical Research Centre, Southmead Hospital, Bristol, UK.

Abstract

Critical illness-related cardiac arrest (CIRCA) as a distinct entity is not well described epidemiologically. There is currently a knowledge gap regarding how many occur in the UK or the impact on patient outcome. The CIRCA study is a prospective multi-centre observational cohort study of patients in the United Kingdom experiencing a cardiac arrest while in a Critical Care Unit embedded in the Case Mix Programme and National Cardiac Arrest Audit. The duration of data collection is 12 months, with surviving patients and family members receiving questionnaire follow-up at 90 days, 180 days and 12 months. This paper describes the protocol for the CIRCA study which received favourable ethical opinion from South Central - Berkshire Research Ethics Committee and approval from the Health Research Authority. Study registration is on clinicaltrials.gov (NCT04219384).

Keywords: Cardiac arrest; critical illness; intensive care; observational study.

Associated data

ClinicalTrials.gov/NCT04219384