Severe Hyponatremia in the Setting of COVID-19-Associated Syndrome of Inappropriate Antidiuretic Hormone: A Case Report

Jorge A Gutierrez; David Ritzenthaler; Angeline Sawaya; Amanda L Pensiero

doi:10.7759/cureus.33330

Severe Hyponatremia in the Setting of COVID-19-Associated Syndrome of Inappropriate Antidiuretic Hormone: A Case Report

Cureus. 2023 Jan 3;15(1):e33330. doi: 10.7759/cureus.33330. eCollection 2023 Jan.

Authors

Jorge A Gutierrez¹, David Ritzenthaler², Angeline Sawaya², Amanda L Pensiero²

Affiliations

¹ Internal Medicine, Case Western Reserve University School of Medicine, Cleveland, USA.
² Internal Medicine, University Hospitals Cleveland Medical Center, Cleveland, USA.

Abstract

The COVID-19 pandemic has resulted in significant worldwide morbidity and mortality. One of the less studied clinical manifestations is Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) associated with COVID-19 pneumonia. We present a single case of COVID-19 pneumonia-associated SIADH in a 71-year-old male with a history of alcohol use disorder. This case highlights the importance of full diagnostic workup of the underlying cause of hyponatremia to avoid significant morbidity.

Keywords: acute hyponatremia; covid 19; covid-19 retro; hyponatremia; syndrome of inappropriate antidiuretic hormone secretion.

Publication types

Case Reports