Chemogenetics for Gene Therapy Based Targeted Cardiac Electrophysiological Modulation

Yehuda Wexler; Matteo Ghiringhelli; Naim Shaheen; Shany Glatstein; Irit Huber; Oded Edri; Yousef Abboud; Michal Landesberg; Daniel Shiff; Gil Arbel; Lior Gepstein

doi:10.1161/CIRCRESAHA.122.322041

Chemogenetics for Gene Therapy Based Targeted Cardiac Electrophysiological Modulation

Circ Res. 2023 Mar 3;132(5):645-647. doi: 10.1161/CIRCRESAHA.122.322041. Epub 2023 Feb 6.

Authors

Affiliations

¹ Sohnis Research Laboratory for Cardiac Electrophysiology and Regenerative Medicine, the Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa, Israel (Y.W., M.G., N.S., S.G., I.H., O.E., Y.A., M.L., D.S., G.A., L.G.).
² Cardiology Department, Rambam Health Care Campus, Haifa, Israel (L.G.).

PMID: 36744466
DOI: 10.1161/CIRCRESAHA.122.322041

No abstract available

Keywords: biological pacemakers; cardiomyocytes; gene therapy, arrhythmia; human-induced pluripotent stem cells; receptors, serotonin; varenicline.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Differentiation
Genetic Therapy
Induced Pluripotent Stem Cells* / physiology
Myocytes, Cardiac* / physiology