Can EAT be an INOCA goalkeeper

Front Endocrinol (Lausanne). 2023 Jan 20:13:1028429. doi: 10.3389/fendo.2022.1028429. eCollection 2022.

Abstract

Ischemia with non-obstructive coronary artery (INOCA) is a blind spot of coronary artery disease (CAD). Such patients are often reassured but offered no specific care, that lead to a heightened risk of adverse cerebrovascular disease (CVD) outcomes. Epicardial adipose tissue (EAT) is proven to correlate independently with CAD and its severity, but it is unknown whether EAT is a specific and sensitive indicator of INOCA. This review focuses on the INOCA epidemiology and related factors, as well as the association between EAT.

Keywords: adipocytokine; coronary microvascular dysfunction; epicardial adipose tissue; inflammatory mediators; ischemic non-obstructive coronary artery disease.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue
  • Coronary Artery Disease* / epidemiology
  • Humans
  • Ischemia
  • Pericardium